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Dr. Stephen G. Withers
Departments of Chemistry,
Biochemistry & Molecular Biology
Centre for High-Throughput Biology

Chemical Biology: Directed Evolution and Inhibitor Screening

The Withers laboratory brings the tools of organic chemistry, biochemistry and molecular biology to bear on the identification, development and evolution of novel biocatalysts, as well as on the development of potent enzyme inhibitors, both by design and by screening. We have a particular interest in the enzymes involved in the assembly and degradation of glycans, with applications ranging from glycoprotein and glycolipid assembly through development of antivirals to biomass conversion.

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